![]() Update on acute kidney injury in the neonate. Neonatal acute kidney injury: pathogenesis, etiology, clinical presentation, and diagnosis. There was a weak negative correlation between serum creatinine and birth weight (r=-0.344 P=0.027).Ĭonclusion Serum creatinine levels in small-for-gestational age newborns are significantly higher than in appropriate-for-gestational age newborns. The median estimated glomerular filtration rates (eGFR) in the small-for-gestational age and appropriate-for-gestational age groups were 25.69 mL/min/1.73m 2 and 30.10 mL/min/1.73m 2 (median difference 4.42 95%CI 2.04 to 15.8 P=0.008), respectively. Mean serum creatinine levels in the small-for-gestational age and appropriate-for-gestational age groups were 0.94 (SD 0.36 95%CI 0.75 to 1.14) mg/dL and 0.69 (SD 0.18 95%CI 0.60 to 0.79) mg/dL (mean difference 0.25 95%CI 0.05 to 0.46 P=0.009), respectively. Result s Of 32 subjects, there were 17 spontaneous deliveries, 14 males, and 18 females. The estimated glomerular filtration rate was calculated based on serum creatinine, infant height, and a proportionality constant using the original Schwartz method, eGFR = /S Cr. ![]() Serum creatinine level was tested by the Jaffe method. The subjects were full term newborn infants consisting of small-for-gestational age and appropriate-for-gestational age groups (16 subjects each), born in Bandung City Regional Public Hospital. Methods This cross-sectional study was conducted in May-June 2018. Objective To determine the usefulness of serum creatinine levels as an estimate of glomerular filtration rate in small-for-gestational age and appropriate-for-gestational age newborns. Serum creatinine levels in newborns are affected by muscle mass, gestational age, as well as the number of nephrons and kidney development. Fetal growth restriction during pregnancy can cause the baby to be born small-for-gestational age. Background The main parameter used to determine renal function in newborns is serum creatinine.
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